Description

Cyclopropane, 1-Bromo-2-Ethenyl-3-Methyl-, (1R,2R,3S)-Rel- (9Ci) is a high-value, stereochemically defined cyclopropane derivative. This compound is a critical chiral building block in advanced organic synthesis, prized for its rigid three-membered ring structure and functional handles for further elaboration. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the construction of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the cyclopropane ring can impart metabolic stability and unique biological activity.
• Material Science Research: Investigated as a monomer or precursor for specialized polymers with potential applications in advanced coatings or electronic materials.
• Asymmetric Catalysis: Employed as a substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its constrained geometry.

Basic Information

Product Name	Cyclopropane, 1-Bromo-2-Ethenyl-3-Methyl-, (1R,2R,3S)-Rel- (9Ci)
CAS No.	681536-82-3
Molecular Formula	C6H9Br
Molecular Weight	161.04 g/mol
Synonyms	1-Bromo-2-ethenyl-3-methylcyclopropane, (1R,2R,3S)-rel-; rel-(1R,2R,3S)-1-Bromo-2-vinyl-3-methylcyclopropane; (1R,2R,3S)-1-Bromo-2-vinyl-3-methylcyclopropane (relative configuration); 1-Bromo-2-vinyl-3-methylcyclopropane; Bromovinylmethylcyclopropane
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols. Every batch is characterized and purified to meet exacting research-grade specifications, with purity typically exceeding 95% (by HPLC or GC). Identity is confirmed via NMR and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing chiral purity, assay, and impurity profile is provided with each shipment to ensure traceability and support your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under an inert atmosphere (e.g., argon or nitrogen), please contact us.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.