Description

Cyclopropane, 1-Bromo-2-Methoxy-3-Methyl-, (1R,2S,3R)-Rel- (9Ci) is a high-purity, stereochemically defined cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its precise three-dimensional structure makes it an invaluable intermediate for constructing complex molecules with defined spatial orientation. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in creating constrained analogs and bioactive molecules.
• Agrochemical Synthesis: Used in the synthesis of advanced, stereoselective pesticides and herbicides where specific spatial configuration impacts biological activity.
• Material Science Research: Employed as a monomer or precursor for developing novel polymers with unique ring-strained architectures.
• Asymmetric Catalysis: Serves as a ligand precursor or a test substrate in the development and optimization of new catalytic systems.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including cyclopropanation reactions and stereochemistry investigations.

Basic Information

Item	Details
Product Name	Cyclopropane, 1-Bromo-2-Methoxy-3-Methyl-, (1R,2S,3R)-Rel- (9Ci)
CAS No.	681536-45-8
Molecular Formula	C5H9BrO
Molecular Weight	165.03 g/mol
Synonyms	(1R,2S,3R)-1-Bromo-2-methoxy-3-methylcyclopropane; rel-(1R,2S,3R)-1-Bromo-2-methoxy-3-methylcyclopropane; 1-Bromo-2-methoxy-3-methylcyclopropane (stereoisomer); Bromomethoxymethylcyclopropane; Cyclopropane, bromomethoxymethyl-; (1R,2S,3R)-1-Bromo-2-methoxy-3-methylcyclopropane (relative configuration)
EINECS	Contact for details

Quality Control

Every batch of Cyclopropane, 1-Bromo-2-Methoxy-3-Methyl-, (1R,2S,3R)-Rel- (9Ci) is produced and tested under strict quality management protocols to ensure identity, purity, and stereochemical integrity. Our rigorous analytical testing includes chiral HPLC, NMR, and GC-MS to confirm specifications. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture uptake and decomposition. Keep away from heat and ignition sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.