Description

Methyl 1,2,3,4-Tetrahydroisoquinoline-4-Carboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of complex molecules, offering a valuable scaffold for medicinal chemistry research and fine chemical manufacturing. It is primarily sought after by pharmaceutical R&D teams and specialty chemical producers for applications in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of bioactive molecules and active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Alkaloid Synthesis: Serves as a fundamental building block for the preparation of complex tetrahydroisoquinoline alkaloids and their analogs.
• Chemical Biology Probes: Employed in the development of molecular probes and tool compounds for studying biological pathways and enzyme functions.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, agrochemicals, and performance materials.

Basic Information

Product Name	Methyl 1,2,3,4-Tetrahydroisoquinoline-4-Carboxylate
CAS No.	681448-82-8
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	Methyl 1,2,3,4-tetrahydro-4-isoquinolinecarboxylate; Methyl 4-carboxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydroisoquinoline-4-carboxylic acid methyl ester; 4-(Methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline; Methyl tetrahydroisoquinoline-4-carboxylate; 4-Carbomethoxy-1,2,3,4-tetrahydroisoquinoline; MTIQC
EINECS	Contact for details

Quality Control

Our Methyl 1,2,3,4-Tetrahydroisoquinoline-4-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.