Description

4-Chloro-6-(4-Fluorophenyl)Thieno[3,2-D]Pyrimidine is a high-value, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique fused-ring structure, incorporating thiophene and pyrimidine motifs with halogen substituents, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for its role in creating molecules with targeted biological and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used as a core scaffold for synthesizing new candidates for herbicides, fungicides, and pesticides.
• Material Science Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its electron-deficient heterocyclic core.
• Chemical Biology Probe: Serves as a starting point for developing molecular probes to study enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects.

Basic Information

Product Name	4-Chloro-6-(4-Fluorophenyl)Thieno[3,2-D]Pyrimidine
CAS No.	681260-56-0
Molecular Formula	C12H6ClFN2S
Molecular Weight	264.70 g/mol
Synonyms	4-Chloro-6-(4-fluorophenyl)thieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine, 4-chloro-6-(4-fluorophenyl)-; 4-Chloro-6-(p-fluorophenyl)thieno[3,2-d]pyrimidine; 681260-56-0; AKOS005258323; BDBM50389317; FT-0698286; SCHEMBL15547627; ZINC000257630716
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-6-(4-Fluorophenyl)Thieno[3,2-D]Pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.