Description

5-Bromo-2-(Triisopropylsilyl)Thiazole is a high-value organosilicon-protected heterocyclic building block, specifically designed for advanced synthetic chemistry. This compound is critical for researchers and process chemists who require precise functionalization and stability in complex molecular construction. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those containing thiazole or brominated heterocyclic cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the thiazole moiety imparts biological activity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, and Stille couplings for carbon-carbon bond formation.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and coordination chemistry.
• Academic & R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Item	Details
Product Name	5-Bromo-2-(Triisopropylsilyl)Thiazole
CAS No.	681218-91-7
Molecular Formula	C13H24BrNSSi
Molecular Weight	334.38 g/mol
Synonyms	5-Bromo-2-(triisopropylsilyl)-1,3-thiazole; 2-(Triisopropylsilyl)-5-bromothiazole; 5-Bromo-2-triisopropylsilylthiazole; TIPS-5-Bromothiazole; 5-Br-2-TIPS-thiazole
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Triisopropylsilyl)Thiazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.