Description

(S,S)-2-Phenyl-2-Chloro-3,4-Dimethyl-5-Phenyl-[1,3,2]-Oxazasilolidine is a high-purity, chiral organosilicon compound of significant interest in advanced synthetic chemistry. This compound matters as a specialized reagent and building block, offering precise stereochemical control for the development of novel pharmaceuticals and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in asymmetric synthesis and catalysis.

Application

• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand in stereoselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Pharmaceutical Intermediates: A key precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Catalyst Development: Serves as a scaffold for developing novel organocatalysts or metal-complexing ligands for homogeneous catalysis.
• Agrochemical Research: Used in the research and development of chiral pesticides and herbicides where specific stereochemistry is crucial for activity.
• Material Science: Investigated as a monomer or additive for creating chiral polymers and advanced silicon-based materials with specific optical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic and organometallic chemistry within university and corporate research laboratories.

Basic Information

Product Name	(S,S)-2-Phenyl-2-Chloro-3,4-Dimethyl-5-Phenyl-[1,3,2]-Oxazasilolidine
CAS No.	680592-40-9
Molecular Formula	C17H18ClNOSi
Molecular Weight	315.87 g/mol
Synonyms	(S,S)-2-Chloro-2-phenyl-3,4-dimethyl-5-phenyl-1,3,2-oxazasilolidine; (4S,5S)-2-Chloro-4,5-dimethyl-2,5-diphenyl-1,3,2-oxazasilolidine; 2-Chloro-4,5-dimethyl-2,5-diphenyl-1,3,2-oxazasilolidine (S,S enantiomer); Chiral Oxazasilolidine Reagent; (S,S)-Oxazasilolidine Chloride; (S,S)-2-Chloro-2-phenyl-3,4-dimethyl-5-phenyl-1,3,2-oxazasilolidine
EINECS	Contact for details

Quality Control

Our (S,S)-2-Phenyl-2-Chloro-3,4-Dimethyl-5-Phenyl-[1,3,2]-Oxazasilolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR, and GC/HPLC for purity assessment, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.