Description

1H-Indole-1-Acetamide, 3-(Hydroxymethyl)-n-Phenyl- is a high-purity, functionalized indole derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable pharmaceutical intermediate and research chemical for developing novel bioactive molecules. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and life science sectors seeking to build complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, and other therapeutic areas.
• Agrochemical Research: Used in the development of new crop protection agents and plant growth regulators due to its indole core structure.
• Chemical Biology & Proteomics: Serves as a precursor for designing enzyme inhibitors, molecular probes, and activity-based protein profiling (ABPP) reagents.
• Material Science: Potential monomer or functional additive in the synthesis of specialized polymers and organic electronic materials.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Item	Detail
Product Name	1H-Indole-1-Acetamide, 3-(Hydroxymethyl)-n-Phenyl-
CAS No.	680585-14-2
Molecular Formula	C₁₇H₁₆N₂O₂
Molecular Weight	280.32 g/mol
Synonyms	3-(Hydroxymethyl)-N-phenyl-1H-indole-1-acetamide; N-Phenyl-3-(hydroxymethyl)indole-1-acetamide; 1-Acetamide, 1H-indole-3-methanol, N-phenyl-; 680585-14-2; 3-Hydroxymethyl-N-phenylindole-1-acetamide
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Acetamide, 3-(Hydroxymethyl)-n-Phenyl- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.