Description

3-(Piperidin-4-Yl)Isoquinolin-1(2H)-One Hydrochloride is a high-purity organic salt compound of significant interest in advanced chemical synthesis. This molecule serves as a critical pharmaceutical intermediate and research chemical for the development of novel bioactive compounds. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and life science sectors seeking to build complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new pharmacophores.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Academic & Institutional R&D: Employed in universities and research institutes for fundamental studies in organic chemistry and heterocyclic compound synthesis.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	3-(Piperidin-4-Yl)Isoquinolin-1(2H)-One Hydrochloride
CAS No.	680223-90-9
Molecular Formula	C14H17ClN2O
Molecular Weight	264.75 g/mol
Synonyms	1(2H)-Isoquinolinone, 3-(4-piperidinyl)-, hydrochloride; 3-(4-Piperidinyl)-1(2H)-isoquinolinone hydrochloride; 3-(Piperidin-4-yl)-1,2-dihydroisoquinolin-1-one hydrochloride; 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1(2H)-isoquinolinone hydrochloride (related base form); PIQ-HCl; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-(Piperidin-4-Yl)Isoquinolin-1(2H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets rigorous standards for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.