Description

1-Acetyl-5-[(4-Chloro-3-Nitrobenzoyl)Amino]Indoline, 5-[(4-Chloro-3-Nitrobenzoyl)Amino]-2,3-Dihydro-1-Ethanoyl-1H-Indole CAS NO 680214-07-7 is a high-purity, advanced pharmaceutical intermediate characterized by its complex indoline-based molecular structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), where its specific substitution pattern enables targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex heterocyclic molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery projects.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Potential use in probing biological pathways and enzyme interactions due to its specific functional groups.

Basic Information

Product Name	1-Acetyl-5-[(4-Chloro-3-Nitrobenzoyl)Amino]Indoline, 5-[(4-Chloro-3-Nitrobenzoyl)Amino]-2,3-Dihydro-1-Ethanoyl-1H-Indole
CAS No.	680214-07-7
Molecular Formula	C18H14ClN3O5
Molecular Weight	387.77 g/mol
Synonyms	1-Acetyl-5-[(4-chloro-3-nitrobenzoyl)amino]indoline; 5-[(4-Chloro-3-nitrobenzoyl)amino]-2,3-dihydro-1-acetyl-1H-indole; 1H-Indole, 5-[(4-chloro-3-nitrobenzoyl)amino]-2,3-dihydro-1-acetyl-; 680214-07-7; N-(1-Acetyl-2,3-dihydro-1H-indol-5-yl)-4-chloro-3-nitrobenzamide; 4-Chloro-3-nitro-N-(1-acetyl-2,3-dihydro-1H-indol-5-yl)benzamide
EINECS	Contact for details

Quality Control

Our 1-Acetyl-5-[(4-Chloro-3-Nitrobenzoyl)Amino]Indoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.