Description

2-Bromo-5-Chloro-1-Benzothiophene-3-Carbaldehyde is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is essential for R&D chemists and process development scientists working in pharmaceutical intermediates, agrochemicals, and functional material discovery.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel small-molecule drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection products, leveraging its halogenated benzothiophene core.
• Organic Electronic Materials: Serves as a building block for π-conjugated systems in the development of organic semiconductors, OLEDs, and sensors.
• Ligand and Catalyst Development: The aldehyde and halogen functionalities allow for derivatization into novel chelating ligands and organocatalysts.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules for studying biological pathways and target engagement.
• Polymer and Resin Modification: Acts as a functional monomer or cross-linking agent for specialty polymers with tailored properties.

Basic Information

Product Name	2-Bromo-5-Chloro-1-Benzothiophene-3-Carbaldehyde
CAS No.	680212-97-9
Molecular Formula	C9H4BrClOS
Molecular Weight	275.55 g/mol
Synonyms	5-Chloro-2-bromobenzothiophene-3-carboxaldehyde; 1-Benzothiophene-3-carboxaldehyde, 2-bromo-5-chloro-; 2-Bromo-5-chlorobenzo[b]thiophene-3-carbaldehyde; 2-Bromo-5-chloro-1-benzothiophene-3-carboxaldehyde; 2-Br-5-Cl-benzothiophene-3-CHO
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-1-Benzothiophene-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.