Description

5-Bromo-8-Fluoroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and fluorine substituents, makes it an invaluable intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new drug candidates, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anticancer drug discovery programs.
• Agrochemical Research: Used as a precursor in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the halogenated isoquinoline scaffold.
• Material Science: Serves as a building block for creating organic light-emitting diodes (OLEDs) and other electronic materials due to its conjugated aromatic system.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Acts as a probe or tag in biochemical research for studying enzyme interactions and cellular processes.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring halogenated heterocycles.

Basic Information

Product Name	5-Bromo-8-Fluoroisoquinoline
CAS No.	679433-94-4
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	8-Fluoro-5-bromoisoquinoline; 5-Bromo-8-fluoro-isoquinoline; Isoquinoline, 5-bromo-8-fluoro-; 679433-94-4; 5-Br-8-F-Isoquinoline
EINECS	Contact for details

Quality Control

Our 5-Bromo-8-Fluoroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.