Description

2-Thiophenecarboxaldehyde, 3-[(1S)-1-Hydroxyethyl]- (9Ci) is a chiral thiophene derivative that serves as a valuable synthetic intermediate in advanced organic chemistry. Its core value lies in its bifunctional structure, combining a reactive aldehyde group with a chiral hydroxyethyl substituent on the thiophene ring, enabling the stereoselective construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of novel, stereospecific pesticides and herbicides.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Material Science Research: Intermediate in the synthesis of functionalized thiophene monomers for conductive polymers and organic electronics.
• Flavor and Fragrance Industry: Potential intermediate for creating complex sulfur-containing aroma molecules.
• Academic and R&D: A versatile chiral synthon for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	2-Thiophenecarboxaldehyde, 3-[(1S)-1-Hydroxyethyl]- (9Ci)
CAS No.	679420-10-1
Molecular Formula	C7H8O2S
Molecular Weight	156.20 g/mol
Synonyms	(S)-3-(1-Hydroxyethyl)thiophene-2-carboxaldehyde; 3-[(1S)-1-Hydroxyethyl]-2-thiophenecarboxaldehyde; (S)-2-Formyl-3-(1-hydroxyethyl)thiophene; 3-(1-Hydroxyethyl)thiophene-2-carbaldehyde (S-isomer); Chiral Thiophene Aldehyde Derivative; (S)-HETCA; 2-Thiophenecarboxaldehyde, 3-(1-hydroxyethyl)-, (S)-
EINECS	Contact for details

Quality Control

Our production of 2-Thiophenecarboxaldehyde, 3-[(1S)-1-Hydroxyethyl]- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment, supporting cGMP and ISO 9001 compliant workflows for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive. Allow the container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.