Description

1-Isobenzofuranol, 1,3-Dihydro-3-Methyl-, (3R)- (9Ci) is a chiral, non-racemic organic compound belonging to the isobenzofuran class, serving as a valuable synthetic intermediate. Its defined stereochemistry at the 3-position makes it a critical building block for the enantioselective synthesis of complex molecules, ensuring high purity and predictable reactivity in downstream processes. This compound is primarily sought by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in creating advanced materials, active pharmaceutical ingredients (APIs), and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Utilized as a precursor or ligand in catalytic asymmetric reactions to construct stereochemically defined complex molecules.
• Fine Chemical Production: Serves as a foundational building block for the manufacture of specialty chemicals, flavors, and fragrances requiring specific enantiomeric purity.
• Agrochemical Research: Employed in the development of new, enantiomerically pure pesticides and herbicides where biological activity is stereospecific.
• Material Science: Investigated as a monomer or modifying agent for creating novel polymers with specific optical or mechanical properties.
• Academic & Industrial R&D: Used in methodological studies and process chemistry development for new synthetic routes.

Basic Information

Product Name	1-Isobenzofuranol, 1,3-Dihydro-3-Methyl-, (3R)- (9Ci)
CAS No.	679420-02-1
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	(3R)-1,3-Dihydro-3-methyl-1-isobenzofuranol; (R)-3-Methylphthalide; (R)-3-Methyl-1(3H)-isobenzofuranone; 3-Methylphthalide, (R)-; (R)-(-)-3-Methylphthalide; 1(3H)-Isobenzofuranone, 3-methyl-, (3R)-; (3R)-3-Methyl-3H-isobenzofuran-1-one
EINECS	Contact for details

Quality Control

Our production of 1-Isobenzofuranol, 1,3-Dihydro-3-Methyl-, (3R)- (9Ci) adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet exacting customer specifications. Certificates of Analysis (COA) are provided, detailing results from analytical methods including HPLC, GC, and chiral analysis. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.