Description

4-Pentynoicacid,2-Amino-2-(Mercaptomethyl)-,(2R)-(9Ci) is a specialized chiral building block containing both amino and thiol functional groups on a pentynoic acid backbone. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those targeting neurological or metabolic pathways.
• Peptidomimetic Synthesis: Used in constructing non-natural amino acid analogs and peptide-like structures for drug discovery programs.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands or organocatalysts due to its multifunctional (NH2, SH) nature.
• Bioconjugation Chemistry: The thiol and alkyne groups enable site-specific conjugation strategies for labeling proteins, antibodies, or other biomolecules.
• Material Science Research: Employed in the development of functionalized polymers or surface coatings where specific molecular recognition or reactivity is desired.
• Chemical Biology Probes: Useful for synthesizing activity-based probes or inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	4-Pentynoicacid,2-Amino-2-(Mercaptomethyl)-,(2R)-(9Ci)
CAS No.	679005-16-4
Molecular Formula	C7H11NO2S
Molecular Weight	173.23 g/mol
Synonyms	(2R)-2-Amino-2-(mercaptomethyl)pent-4-ynoic acid; D-2-Amino-2-(mercaptomethyl)pent-4-ynoic acid; (R)-2-Amino-2-(mercaptomethyl)-4-pentynoic acid; 2-Amino-2-(mercaptomethyl)-4-pentynoic acid, (2R)-; 679005-16-4; (R)-HomoCys(Alkyne); A building block for constrained peptide synthesis
EINECS	Contact for details

Quality Control

Every batch of 4-Pentynoicacid,2-Amino-2-(Mercaptomethyl)-,(2R)-(9Ci) is produced and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Certificates of Analysis (COA) detailing purity, chiral purity, and identity are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. This material is moisture-sensitive; keep the container tightly sealed in a cool, dry place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.