Description

4-(2-Chlorophenyl)-6-Methylthieno[2,3-D]Pyrimidin-2(1H)-One is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key synthetic intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile scaffold for molecular diversification. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activities.

Application

This specialized chemical intermediate serves critical roles in research and industrial synthesis:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique thienopyrimidine core.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study biological pathways and protein functions.
• Material Science Research: Investigated as a building block for organic electronic materials due to its fused heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Used in university and government labs for fundamental studies in heterocyclic and medicinal chemistry.

Basic Information

Item	Detail
Product Name	4-(2-Chlorophenyl)-6-Methylthieno[2,3-D]Pyrimidin-2(1H)-One
CAS No.	677713-46-1
Molecular Formula	C13H9ClN2OS
Molecular Weight	276.74 g/mol
Synonyms	4-(2-Chlorophenyl)-6-methyl-1H-thieno[2,3-d]pyrimidin-2-one; 6-Methyl-4-(2-chlorophenyl)thieno[2,3-d]pyrimidin-2(1H)-one; Thieno[2,3-d]pyrimidin-2(1H)-one, 4-(2-chlorophenyl)-6-methyl-; CAS 677713-46-1; 4-(2-Chlorophenyl)-6-methylthieno[2,3-d]pyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our production of 4-(2-Chlorophenyl)-6-Methylthieno[2,3-D]Pyrimidin-2(1H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure consistency and meet the exacting standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.