Description

1-(Phenylsulfonyl)-4-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonylated azaindole core structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel, biologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology and inflammatory disease pathways.
• Kinase Inhibitor Scaffold: Serves as a core structural motif for designing and synthesizing selective kinase inhibitors due to the privileged azaindole pharmacophore.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to improve potency and pharmacokinetic properties.
• Biochemical Probe Development: Employed in the creation of tool compounds for investigating specific biological targets and signaling pathways in vitro.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	1-(Phenylsulfonyl)-4-Azaindole
CAS No.	677302-44-2
Molecular Formula	C13H10N2O2S
Molecular Weight	258.30 g/mol
Synonyms	1-(Benzenesulfonyl)-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine, 1-(phenylsulfonyl)-; 4-Azaindole, 1-(phenylsulfonyl)-; 1-Phenylsulfonyl-1H-pyrrolo[3,2-b]pyridine; 1-(Phenylsulfonyl)-1H-pyrrolo[3,2-b]pyridine; 1-Benzenesulfonyl-4-azaindole; 1-(Phenylsulfonyl)-4-aza-indole
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-4-Azaindole is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.