Description

8-Indolizineethanol,5,6,7,8-Tetrahydro-,(8R)-(9Ci) is a high-purity chiral indolizine derivative, a specialized organic building block of significant interest in advanced synthetic chemistry. Its defined stereochemistry and functionalized structure make it a valuable precursor for the development of novel pharmacologically active compounds. This material is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the synthesis of complex heterocyclic molecules, where precise stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Fine Chemical Production: Utilized in the multi-step synthesis of other high-value, complex fine chemicals and specialty materials.

Basic Information

Product Name	8-Indolizineethanol,5,6,7,8-Tetrahydro-,(8R)-(9Ci)
CAS No.	677005-72-0
Molecular Formula	C10H15NO
Molecular Weight	165.23 g/mol
Synonyms	(8R)-5,6,7,8-Tetrahydro-8-indolizineethanol; (R)-5,6,7,8-Tetrahydro-8-(2-hydroxyethyl)indolizine; 8-(2-Hydroxyethyl)-5,6,7,8-tetrahydroindolizine, (8R)-; Tetrahydroindolizine ethanol derivative (R)-isomer; Chiral indolizine ethanol; 8R-THI-EtOH; (R)-8-(2-Hydroxyethyl)-1,2,3,5,6,7,8,8a-octahydroindolizine
EINECS	Contact for details

Quality Control

Our 8-Indolizineethanol,5,6,7,8-Tetrahydro-,(8R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.