Description

8-Indolizineacetaldehyde,5,6,7,8-Tetrahydro-,(8R)-(9Ci) is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex bioactive molecules, particularly in medicinal chemistry and asymmetric synthesis. It is primarily needed by research institutions and pharmaceutical companies developing novel therapeutic agents, including potential candidates for neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Asymmetric Synthesis: Serves as a valuable precursor for constructing complex, enantiomerically pure heterocyclic compounds.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and enzyme functions.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential clinical trial materials.

Basic Information

Product Name	8-Indolizineacetaldehyde,5,6,7,8-Tetrahydro-,(8R)-(9Ci)
CAS No.	677005-71-9
Molecular Formula	C10H15NO
Molecular Weight	165.23 g/mol
Synonyms	(8R)-5,6,7,8-Tetrahydro-8-indolizineacetaldehyde; (R)-5,6,7,8-Tetrahydroindolizine-8-acetaldehyde; (R)-Octahydroindolizine-8-acetaldehyde; (8R)-Octahydroindolizine-8-acetaldehyde; (R)-THIA; (R)-Tetrahydroindolizineacetaldehyde; (R)-8-Indolizineacetaldehyde,5,6,7,8-tetrahydro-; (R)-Enantiomer of 5,6,7,8-Tetrahydroindolizine-8-acetaldehyde
EINECS	Contact for details

Quality Control

Our 8-Indolizineacetaldehyde,5,6,7,8-Tetrahydro-,(8R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and light-sensitive.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.