Description

3-(2-Acetyl-5-tert-Butyl-Thiophen-3-Ylcarbamoyl)-Acrylic Acid CAS NO 676996-35-3 is a high-purity, specialized organic intermediate featuring a unique thiophene-acrylic acid hybrid structure. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific functional groups enable precise molecular modifications. It is primarily needed by research and development chemists, process scale-up engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, coatings, or organic electronic materials.
• Chemical Biology Probes: Employed in the creation of labeled compounds or probes for studying biological pathways and mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical and custom synthesis houses serving diverse R&D projects.

Basic Information

Product Name	3-(2-Acetyl-5-tert-Butyl-Thiophen-3-Ylcarbamoyl)-Acrylic Acid
CAS No.	676996-35-3
Molecular Formula	C14H17NO4S
Molecular Weight	295.35 g/mol
Synonyms	3-[(2-Acetyl-5-tert-butylthiophen-3-yl)carbamoyl]acrylic acid; 2-Propenoic acid, 3-[[(2-acetyl-5-(1,1-dimethylethyl)-3-thienyl)amino]carbonyl]-; (E)-3-((2-Acetyl-5-(tert-butyl)thiophen-3-yl)carbamoyl)acrylic acid; 3-(2-Acetyl-5-tert-butylthiophene-3-carboxamido)acrylic acid; tert-Butyl acetyl thiophene acrylamide carboxylic acid; Acrylic acid derivative of 2-acetyl-5-tert-butylthiophene-3-carboxamide; TBCA Intermediate
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Acetyl-5-tert-Butyl-Thiophen-3-Ylcarbamoyl)-Acrylic Acid is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.