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1-(3-Fluorophenyl)-2,5-Dimethyl-1H-Pyrrole-3-Methanol CAS NO 676641-33-1


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CAS No.:676641-33-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(3-Fluorophenyl)-2,5-Dimethyl-1H-Pyrrole-3-Methanol is a high-purity fluorinated pyrrole derivative, a versatile and valuable building block in advanced organic synthesis. Its molecular structure, featuring a fluorinated aromatic ring and a hydroxymethyl substituent, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical developers for applications in medicinal chemistry and material science.

Application

  • Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
  • Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
  • Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
  • Chemical Synthesis: Employed as a versatile scaffold in medicinal and combinatorial chemistry for library synthesis and structure-activity relationship (SAR) studies.
  • Fluorine Chemistry: Utilized as a standard or reagent in methodological development for introducing fluorinated motifs into complex molecular architectures.

Basic Information

Product Name 1-(3-Fluorophenyl)-2,5-Dimethyl-1H-Pyrrole-3-Methanol
CAS No. 676641-33-1
Molecular Formula C13H14FNO
Molecular Weight 219.26 g/mol
Synonyms 3-(Hydroxymethyl)-1-(3-fluorophenyl)-2,5-dimethyl-1H-pyrrole; 1-(3-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-methanol; 1H-Pyrrole-3-methanol, 1-(3-fluorophenyl)-2,5-dimethyl-; (1-(3-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methanol; 3-Hydroxymethyl-1-(3-fluorophenyl)-2,5-dimethylpyrrole
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Quality Control

Our 1-(3-Fluorophenyl)-2,5-Dimethyl-1H-Pyrrole-3-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications in GMP-oriented development and other regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Related Substances (HPLC) Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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