Description

2,3-Dioxabicyclo[2.2.2]Oct-7-En-5-Ol,Acetate,(1S,4S,5S)-(9Ci) is a high-purity, stereochemically defined bicyclic compound with the CAS number 676543-80-9. This molecule is valued for its unique bridged structure and functional groups, making it a versatile and critical chiral building block in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for the construction of complex, biologically active molecules.

Application

This specialized chiral intermediate is utilized in sophisticated synthetic pathways. Key application areas include:

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to introduce specific stereocenters with high enantiomeric purity.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Fine Chemical Production: Acts as a precursor in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring precise stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for creating molecular libraries.

Basic Information

Product Name	2,3-Dioxabicyclo[2.2.2]Oct-7-En-5-Ol,Acetate,(1S,4S,5S)-(9Ci)
CAS No.	676543-80-9
Molecular Formula	C9H10O4
Molecular Weight	182.17 g/mol
Synonyms	(1S,4S,5S)-7-Oxabicyclo[2.2.2]oct-5-en-2,3-diol, 5-acetate; (1S,4S,5S)-5-(Acetyloxy)-2,3-dioxabicyclo[2.2.2]oct-7-ene; (1S,4S,5S)-Bicyclo[2.2.2]oct-7-ene-2,3-diol, 5-acetate; (1S,4S,5S)-5-Acetoxy-2,3-dioxabicyclo[2.2.2]oct-7-ene; Chiral Dioxabicyclooctene Acetate; (1S,4S,5S)-enantiomer of CAS 676543-80-9
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral GC/HPLC, and NMR spectroscopy. A detailed Certificate of Analysis (COA) documenting identity, purity, chiral purity, and impurity profile is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere if specified for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC/GC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.