Description

7-Thiabicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, (1R,2S,4R)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic sulfur-containing aldehyde building block. This compound matters as a sophisticated chiral synthon, enabling the synthesis of complex molecules with precise three-dimensional architecture. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral targets.
• Agrochemical Research: Used to build complex molecular scaffolds for the development of new pesticides and herbicides with enhanced activity.
• Ligand Synthesis: Serves as a starting material for creating chiral ligands used in asymmetric catalysis.
• Material Science: A building block for advanced polymers and functional materials where the rigid bicyclic structure imparts specific properties.
• Academic & R&D: Employed in methodological chemistry research to explore new synthetic pathways and reaction mechanisms.
• Custom Synthesis: A critical component for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	7-Thiabicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, (1R,2S,4R)-Rel- (9Ci)
CAS No.	676520-09-5
Molecular Formula	C7H8OS
Molecular Weight	140.20 g/mol
Synonyms	(1R,2S,4R)-7-Thiabicyclo[2.2.1]hept-5-ene-2-carboxaldehyde; rel-(1R,2S,4R)-7-Thiabicyclo[2.2.1]hept-5-ene-2-carbaldehyde; Bicyclic Thioether Aldehyde; 7-Thianorbornene-2-carboxaldehyde derivative; Chiral Thiabicycloheptene Carboxaldehyde; CAS 676520-09-5; (1R,2S,4R)-rel-7-Thiabicyclo[2.2.1]hept-5-ene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 7-Thiabicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, (1R,2S,4R)-Rel- (9Ci) undergoes rigorous analytical characterization to ensure identity, purity, and stereochemical integrity. Our quality protocols are designed to meet the stringent requirements of research and pre-clinical development. Certificates of Analysis (COA) detailing purity by HPLC, chiral purity, and full spectroscopic data (NMR, IR, MS) are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere for prolonged manipulations to ensure long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.