Description

7-Azabicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde,(1R,2R,4R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic aldehyde building block. This compound is valued for its rigid, three-dimensional scaffold and reactive aldehyde functionality, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) or requiring specific three-dimensional pharmacophores.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where its bicyclic structure can contribute to unique biological activity and stability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Material Science Monomer: Potential building block for creating specialty polymers with unique thermal or mechanical properties due to its strained bicyclic framework.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for methodological development and exploring new chemical space in medicinal chemistry.

Basic Information

Item	Details
Product Name	7-Azabicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde,(1R,2R,4R)-Rel-(9Ci)
CAS No.	676520-00-6
Molecular Formula	C7H9NO
Molecular Weight	123.15 g/mol
Synonyms	(1R,2R,4R)-7-Azabicyclo[2.2.1]hept-5-ene-2-carboxaldehyde; (1R,2R,4R)-7-Azabicyclo[2.2.1]hept-5-ene-2-carbaldehyde; rel-(1R,2R,4R)-7-Azabicyclo[2.2.1]hept-5-ene-2-carboxaldehyde; Bicyclic Aldehyde Intermediate 676520-00-6; 7-Azanorbornene-2-carboxaldehyde derivative; (1R,2R,4R)-rel-2-Formyl-7-azabicyclo[2.2.1]hept-5-ene
EINECS	Contact for details

Quality Control

Every batch of 7-Azabicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde,(1R,2R,4R)-Rel-(9Ci) is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure compliance with exacting purity and stereochemical integrity standards required for advanced R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), chiral purity, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (rel-(1R,2R,4R))
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.