Description

2,2,2-Trifluoro-1-(6-Methoxy-1H-Indol-3-Yl)Ethan-1-One is a high-purity, fluorinated indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceuticals and agrochemicals, particularly those targeting specific biological pathways. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry and material science. The precise trifluoromethyl ketone moiety offers unique reactivity and physicochemical properties essential for creating molecules with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Medicinal Chemistry Research: Used as a versatile scaffold for drug discovery and lead optimization programs, especially in central nervous system (CNS) and oncology research.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with improved efficacy and environmental profiles.
• Fluorinated Compound Synthesis: Essential for introducing the trifluoromethyl group into complex organic molecules to modulate their lipophilicity and metabolic stability.
• Material Science Precursor: Potential use in the development of advanced organic electronic materials and specialty polymers.
• Biochemical Probe Synthesis: Used to create labeled compounds or probes for studying biological mechanisms and enzyme interactions.

Basic Information

Product Name	2,2,2-Trifluoro-1-(6-Methoxy-1H-Indol-3-Yl)Ethan-1-One
CAS No.	676476-94-1
Molecular Formula	C11H8F3NO2
Molecular Weight	243.18 g/mol
Synonyms	6-Methoxy-3-(2,2,2-trifluoroacetyl)indole; 3-(Trifluoroacetyl)-6-methoxy-1H-indole; 1-(6-Methoxy-1H-indol-3-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(6-methoxy-1H-indol-3-yl)ethanone; 6-Methoxy-3-trifluoroacetylindole; TFMOI; Trifluoroacetyl-6-methoxyindole
EINECS	Contact for details

Quality Control

Every batch of 2,2,2-Trifluoro-1-(6-Methoxy-1H-Indol-3-Yl)Ethan-1-One is manufactured and tested under strict quality management systems. We ensure compliance with relevant industry standards for research and pharmaceutical-grade intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.