Description

3-Cyano-1H-Indol-5-Ylboronic Acid is a high-value, multifunctional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This advanced building block is critically needed by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel indole-based compounds, including potential drug candidates and agrochemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex indole scaffolds in active pharmaceutical ingredients (APIs) and drug discovery libraries.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for palladium-catalyzed reactions to form biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides featuring indole motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as novel semiconductors and light-emitting compounds.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Catalyst Ligand Precursor: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	3-Cyano-1H-Indol-5-Ylboronic Acid
CAS No.	676273-51-1
Molecular Formula	C9H7BN2O2
Molecular Weight	186.98 g/mol
Synonyms	5-Borono-1H-indole-3-carbonitrile; (3-Cyano-1H-indol-5-yl)boronic acid; 3-Cyano-5-indoleboronic acid; 1H-Indole-3-carbonitrile, 5-borono-; 5-(3-Cyano-1H-indol-5-yl)boronic acid; Boronic acid, B-(3-cyano-1H-indol-5-yl)-; CAS 676273-51-1
EINECS	Contact for details

Quality Control

Our 3-Cyano-1H-Indol-5-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). For long-term storage, consider storing at 2-8°C. Keep the container tightly sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.