Description

4-(1-Adamantyl)Pyrimidine-2-Thiol is a specialized organic compound featuring a unique adamantane-pyrimidine hybrid structure. This molecular architecture makes it a valuable intermediate for the development of novel materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing compounds with enhanced stability and specific biological or physical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring high metabolic stability.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, leveraging the adamantyl group's influence on lipophilicity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers, coatings, or liquid crystals with tailored thermal and mechanical properties.
• Ligand Synthesis: The thiol and pyrimidine functionalities make it a useful precursor for creating complex ligands in coordination chemistry and catalysis.
• Chemical Biology Probe Development: Employed in designing molecular probes to study enzyme function or protein interactions due to its distinctive steric profile.

Basic Information

Product Name	4-(1-Adamantyl)Pyrimidine-2-Thiol
CAS No.	676270-45-4
Molecular Formula	C14H18N2S
Molecular Weight	246.37 g/mol
Synonyms	4-(1-Adamantyl)-2-pyrimidinethiol; 4-(Tricyclo[3.3.1.13,7]dec-1-yl)pyrimidine-2-thiol; 2-Mercapto-4-(1-adamantyl)pyrimidine; 4-Adamantyl-2-pyrimidinethiol; 2-Pyrimidinethiol, 4-(1-adamantyl)-; 4-(1-Adamantyl)-2-mercaptopyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-(1-Adamantyl)Pyrimidine-2-Thiol is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and process development. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its property of being easily oxidized, this material should be stored under an inert atmosphere (e.g., nitrogen or argon). Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.