Description

6-Bromo-4-Isochromanone is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its unique brominated isochromanone scaffold.
• Material Science Precursor: Serves as a building block for organic electronic materials, ligands for catalysis, and advanced polymers.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including novel cyclization and cross-coupling reactions.
• Custom Synthesis: Employed by fine chemical manufacturers for the bespoke production of complex molecules for client-specific projects.

Basic Information

Product Name	6-Bromo-4-Isochromanone
CAS No.	676134-68-2
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	6-Bromo-3,4-dihydro-1H-2-benzopyran-4-one; 6-Bromo-4-chromanone; 4-Isochromanone, 6-bromo-; 6-Bromo-3,4-dihydroisocoumarin; 6-Bromo-3,4-dihydro-1H-isochromen-4-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Isochromanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.