Description

(S)-1-Pyrrolidin-2-(1'H-Indol-3'Ylmethyl)-2-(n-Cbz-n-Methyl)Amino-Ethane is a sophisticated chiral intermediate of significant importance in modern pharmaceutical research and development. This compound is valued for its structural complexity, which makes it a key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel therapeutic agents. It is primarily sought by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of new drugs, particularly those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities, especially in high-throughput screening and structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Serves as a key precursor in stereoselective synthesis routes due to its defined (S)-configuration.
• Peptidomimetic Development: Its structure, containing indole and protected amine functionalities, makes it valuable for creating peptide-like molecules with enhanced stability and bioavailability.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	(S)-1-Pyrrolidin-2-(1'H-Indol-3'Ylmethyl)-2-(n-Cbz-n-Methyl)Amino-Ethane
CAS No.	675602-66-1
Molecular Formula	C24H29N3O2
Molecular Weight	391.51 g/mol
Synonyms	(S)-2-[(1H-Indol-3-yl)methyl]-1-[(benzyloxy)carbonyl(methyl)amino]-N-(pyrrolidin-1-yl)ethanamine; (S)-N-Cbz-N-Methyl-1-(1H-indol-3-ylmethyl)-2-(pyrrolidin-1-yl)ethane-1,2-diamine; 675602-66-1; (S)-1-Pyrrolidin-2-(1'H-Indol-3'Ylmethyl)-2-(n-Carbobenzoxy-n-Methyl)Amino-Ethane; (S)-N-Cbz-N-Methyl-1-(indol-3-ylmethyl)-2-(pyrrolidin-1-yl)ethane-1,2-diamine; Chiral Indole-Pyrrolidine Derivative; Cbz-Protected Amino Ethane Intermediate
EINECS	Contact for details

Quality Control

Every batch of (S)-1-Pyrrolidin-2-(1'H-Indol-3'Ylmethyl)-2-(n-Cbz-n-Methyl)Amino-Ethane is produced and tested under strict quality management systems. Our products undergo rigorous analytical testing to ensure high purity, chiral integrity, and consistency, meeting the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.