Description

1H-Isoindol-1-One, 2,3-Dihydro-6-Iodo- is a halogenated isoindolinone derivative, a high-value chemical intermediate prized for its role in constructing complex molecular architectures. Its core value lies in enabling precise synthetic pathways in advanced research and development, particularly where the introduction of an iodine atom is critical for further functionalization. This compound is essential for pharmaceutical chemists and agrochemical researchers developing novel active ingredients, as well as for material scientists working on specialty polymers and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that require halogenated heterocyclic cores.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the production of specialty polymers, dyes, and pigments with specific optical or electronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactivity of the iodine substituent, facilitating carbon-carbon bond formation.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Ligand & Catalyst Development: Acts as a precursor for creating novel ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1H-Isoindol-1-One, 2,3-Dihydro-6-Iodo-
CAS No.	675109-30-5
Molecular Formula	C8H6INO
Molecular Weight	259.05 g/mol
Synonyms	6-Iodo-2,3-dihydro-1H-isoindol-1-one; 6-Iodoisoindolin-1-one; 2,3-Dihydro-6-iodo-1H-isoindol-1-one; 1H-Isoindol-1-one, 2,3-dihydro-6-iodo-; 675109-30-5; AI3-32936; SCHEMBL218062; BCP31033; ZINC000004092756
EINECS	Contact for details

Quality Control

Our 1H-Isoindol-1-One, 2,3-Dihydro-6-Iodo- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. For custom synthesis projects, we adhere to cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.