Description

6-Bromoisoindolin-1-One is a versatile brominated isoindolinone derivative, a key synthetic intermediate in modern organic chemistry. Its value lies in its reactive bromine substituent, which enables efficient cross-coupling reactions and functional group transformations essential for constructing complex molecular architectures. This high-purity building block is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its heterocyclic core structure.
• Material Science: Serves as a precursor for organic electronic materials, such as charge-transport layers or organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the isoindolinone moiety into more complex molecules.
• Ligand and Catalyst Development: Acts as a scaffold for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic routes in university and industrial research laboratories.

Basic Information

Product Name	6-Bromoisoindolin-1-One
CAS No.	675109-26-9
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	6-Bromo-2,3-dihydro-1H-isoindol-1-one; 6-Bromo-isoindolin-1-one; 1H-Isoindol-1-one, 6-bromo-2,3-dihydro-; 6-Bromoisoindolinone; 6-Bromo-1-isoindolinone; 6-Bromo-2,3-dihydroisoindol-1-one
EINECS	Contact for details

Quality Control

Our 6-Bromoisoindolin-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.