Description

4,5,6,7-Tetrahydro-2-[3-(Hydroxymethyl)-2,5-Dimethyl-1H-Pyrrol-1-Yl]-Benzo[B]Thiophene-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and serves as a versatile building block in medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Agrochemical Development: Serves as a precursor for creating new active ingredients in crop protection products.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic frameworks in academic and industrial laboratories.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	4,5,6,7-Tetrahydro-2-[3-(Hydroxymethyl)-2,5-Dimethyl-1H-Pyrrol-1-Yl]-Benzo[B]Thiophene-3-Carbonitrile
CAS No.	674788-80-8
Molecular Formula	C17H20N2OS
Molecular Weight	300.42 g/mol
Synonyms	Benzo[b]thiophene-3-carbonitrile, 4,5,6,7-tetrahydro-2-[3-(hydroxymethyl)-2,5-dimethyl-1H-pyrrol-1-yl]-; 2-(3-(Hydroxymethyl)-2,5-dimethyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile; 4,5,6,7-Tetrahydro-2-(3-(hydroxymethyl)-2,5-dimethylpyrrol-1-yl)benzo[b]thiophene-3-carbonitrile; CAS 674788-80-8
EINECS	Contact for details

Quality Control

Our production of 4,5,6,7-Tetrahydro-2-[3-(Hydroxymethyl)-2,5-Dimethyl-1H-Pyrrol-1-Yl]-Benzo[B]Thiophene-3-Carbonitrile adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.