Description

5-Amino-2-Carboxy-4-Cyano-3-Thiopheneacetic Acid is a high-value, multifunctional heterocyclic building block with significant synthetic utility. Its unique structure, featuring amino, carboxy, cyano, and acetic acid substituents on a thiophene core, makes it a versatile precursor for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in the development of kinase inhibitors, antiviral agents, and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its thiophene scaffold for bioactivity.
• Material Science: Serves as a monomer or precursor for conductive polymers, organic semiconductors, and other functional materials due to the electron-rich thiophene unit.
• Dye and Pigment Chemistry: Employed in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.
• Chemical Research: A valuable building block in organic synthesis for constructing complex, polyfunctionalized heterocyclic systems for discovery chemistry.
• Ligand and Catalyst Development: The multiple coordination sites make it a candidate for developing novel chelating ligands and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Amino-2-Carboxy-4-Cyano-3-Thiopheneacetic Acid
CAS No.	674773-14-9
Molecular Formula	C8H6N2O4S
Molecular Weight	226.21 g/mol
Synonyms	3-Thiopheneacetic acid, 5-amino-2-carboxy-4-cyano-; 5-Amino-4-cyano-2-thiophenecarboxylic acid, acetic acid derivative; 2-(5-Amino-2-carboxy-4-cyano-3-thienyl)acetic acid; ACCA (abbreviation); 5-Amino-4-cyano-2-thiophenecarboxylic acid acetic acid; Thiophene-3-acetic acid, 5-amino-2-carboxy-4-cyano-; Polyfunctional thiophene acetic acid derivative
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Carboxy-4-Cyano-3-Thiopheneacetic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates, including cGMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is compatible with strong acid/organic solvent conditions but should be handled with standard laboratory precautions. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.