Description

5-Fluoro-2-(trichloromethyl)-1H-benzimidazole is a specialized halogenated benzimidazole derivative, a key heterocyclic building block prized for its unique molecular architecture. This compound matters for its role as a crucial synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals, where its structure enables the introduction of specific functional groups. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting viral infections and certain cancers.
• Agrochemical Synthesis: Used in the research and development of new-generation fungicides and herbicides, leveraging the bioactivity of the benzimidazole core.
• Organic Synthesis Building Block: A versatile reagent for constructing complex heterocyclic systems in academic and industrial research settings.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique electronic or thermal properties.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	5-Fluoro-2-(Trichloromethyl)-1H-Benzimidazole
CAS No.	673487-34-8
Molecular Formula	C8H4Cl3FN2
Molecular Weight	259.49 g/mol
Synonyms	5-Fluoro-2-(trichloromethyl)-1H-benzo[d]imidazole; 2-(Trichloromethyl)-5-fluoro-1H-benzimidazole; 1H-Benzimidazole, 5-fluoro-2-(trichloromethyl)-; 5-Fluoro-2-trichloromethylbenzimidazole; 673487-34-8; FC-BIM; Trichloromethyl-fluoro-benzimidazole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(trichloromethyl)-1H-benzimidazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.