Description

1H-Benzimidazole-4-Carboxylicacid,1-Methyl-(9Ci) is a high-purity, functionalized benzimidazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily utilized by pharmaceutical R&D teams and custom synthesis organizations focused on creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new fungicides and herbicides due to the bioactive benzimidazole core.
• Material Science: Serves as a monomer or ligand for constructing advanced polymers and metal-organic frameworks (MOFs).
• Organic Synthesis Building Block: The carboxylic acid functionality allows for further derivatization (amidation, esterification) to create diverse chemical libraries.
• Biochemical Research: Employed in the study of protein-ligand interactions and as a scaffold for probe molecule development.

Basic Information

Product Name	1H-Benzimidazole-4-Carboxylicacid,1-Methyl-(9Ci)
CAS No.	672957-92-5
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	1-Methyl-1H-benzimidazole-4-carboxylic acid; 1-Methyl-4-carboxybenzimidazole; 4-Carboxy-1-methylbenzimidazole; 1-Methylbenzimidazole-4-carboxylic acid; 672957-92-5; 1-Methyl-1H-benzo[d]imidazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1H-Benzimidazole-4-Carboxylicacid,1-Methyl-(9Ci) adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.