Description

2-((2-[2-(Trifluoromethyl)-1H-1,3-Benzimidazol-1-Yl]Acetyl)Amino)Benzenecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzimidazole core linked to a benzoic acid moiety via an acetamide bridge. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzyme pathways. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, especially in oncology and antiviral research.
• Biochemical Research: Used as a standard or reagent in enzymatic and receptor-binding studies due to its specific molecular structure.
• Protease Inhibitor Development: The benzimidazole scaffold is valuable for creating molecules that inhibit specific protease enzymes.
• Ligand Synthesis: Employed in the development of specialized ligands for medicinal chemistry and diagnostic applications.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Utilized in university laboratories for investigating structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	2-((2-[2-(Trifluoromethyl)-1H-1,3-Benzimidazol-1-Yl]Acetyl)Amino)Benzenecarboxylic Acid
CAS No.	672950-89-9
Molecular Formula	C17H12F3N3O3
Molecular Weight	363.29 g/mol
Synonyms	2-({[2-(2-Trifluoromethyl-1H-benzimidazol-1-yl)]acetyl}amino)benzoic acid; N-[2-(2-Trifluoromethylbenzimidazol-1-yl)acetyl]anthranilic acid; 2-[[2-(2-Trifluoromethylbenzimidazol-1-yl)acetyl]amino]benzoic acid; 2-((2-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-1-yl)acetyl)amino)benzoic acid; 672950-89-9; Benzoic acid, 2-[[[2-[2-(trifluoromethyl)-1H-benzimidazol-1-yl]acetyl]amino]-; Anthranilic acid, N-[2-(2-trifluoromethylbenzimidazol-1-yl)acetyl]-
EINECS	Contact for details

Quality Control

Our 2-((2-[2-(Trifluoromethyl)-1H-1,3-Benzimidazol-1-Yl]Acetyl)Amino)Benzenecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.