Description

1H-Indene-1-Methanol,Octahydro-2-Hydroxy-1,3-Dimethyl-,(1R,2S,3S,3Ar,7Ar)-Rel-(9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a sophisticated building block in the development of complex, biologically active molecules, where its specific stereochemistry is critical for function. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by fine chemical manufacturers specializing in custom synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring complex polycyclic frameworks.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the defined spatial orientation of the molecule enhances biological activity.
• Fine Chemical Manufacturing: Serves as a premium building block for custom synthesis and contract manufacturing of specialty chemicals.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new catalytic methodologies.
• Fragrance and Flavor Chemistry: Potential use in the synthesis of complex, high-value odorants and flavorants due to its unique indane-derived structure.
• Material Science Research: Investigated as a monomer or precursor for novel polymers with specific optical or mechanical properties.

Basic Information

Product Name	1H-Indene-1-Methanol,Octahydro-2-Hydroxy-1,3-Dimethyl-,(1R,2S,3S,3Ar,7Ar)-Rel-(9Ci)
CAS No.	672936-75-3
Molecular Formula	C12H22O2
Molecular Weight	198.30 g/mol
Synonyms	(1R,2S,3S,3aR,7aR)-Octahydro-2-hydroxy-1,3-dimethyl-1H-indene-1-methanol; rel-(1R,2S,3S,3aR,7aR)-Octahydro-2-hydroxy-1,3-dimethyl-1H-indene-1-methanol; Octahydro-2-hydroxy-1,3-dimethyl-1H-indene-1-methanol, (1R,2S,3S,3aR,7aR)-rel-; 1H-Indene-1-methanol, octahydro-2-hydroxy-1,3-dimethyl-, (1R,2S,3S,3aR,7aR)-rel-; CAS 672936-75-3
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, typically exceeding 97% (by HPLC). Identity and stereochemical purity are confirmed via advanced analytical techniques including NMR, HPLC, and chiral chromatography. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.