Description

Bicyclo[2.2.2]Octane-2,6-Diol, 2-Phenyl-, (1R,2R,4S,6S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid bicyclic framework and multiple functional handles make it a valuable scaffold for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric catalysis, medicinal chemistry, and the development of novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system.
• Asymmetric Catalyst Ligand: The diol and phenyl groups can be modified to create novel ligands for transition metal catalysis, enabling enantioselective transformations.
• Advanced Material Synthesis: Used as a building block for polymers and dendrimers with specific rigid geometries and optical properties.
• Agrochemical Research: Employed in the development of new chiral pesticides and herbicides where stereochemistry impacts biological activity.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and for probing structure-activity relationships.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-2,6-Diol, 2-Phenyl-, (1R,2R,4S,6S)-Rel- (9Ci)
CAS No.	670248-34-7
Molecular Formula	C14H18O2
Molecular Weight	218.29 g/mol
Synonyms	(1R,2R,4S,6S)-2-Phenylbicyclo[2.2.2]octane-2,6-diol; rel-(1R,2R,4S,6S)-2-Phenylbicyclo[2.2.2]octane-2,6-diol; 2-Phenylbicyclo[2.2.2]octane-2,6-diol (rel-(1R,2R,4S,6S)-form); Bicyclo[2.2.2]octane-2,6-diol, 2-phenyl-, (1R,2R,4S,6S)-rel-; 670248-34-7
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octane-2,6-Diol, 2-Phenyl-, (1R,2R,4S,6S)-Rel- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical assay, and impurity profile. We support cGMP compliance for advanced intermediates and can provide material for FDA-filed projects upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.