Description

Ethyl 2-[(Cyanoacetyl)Amino]-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 669753-36-0. This compound is valued for its role as a critical building block in the synthesis of complex heterocyclic molecules, offering precise structural control for research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated fused-ring systems.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those with fused thiophene and cycloheptane motifs.
• Organic Synthesis Building Block: Used in research to construct complex heterocyclic frameworks for medicinal chemistry and material science applications.
• API Development: Serves as a critical scaffold in the development of new Active Pharmaceutical Ingredients (APIs) targeting central nervous system (CNS) disorders, anti-inflammatory agents, or other specialized therapeutics.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Utilized in the controlled, scaled-up manufacture of specialty chemicals requiring high regioselectivity and purity.

Basic Information

Item	Details
Product Name	Ethyl 2-[(Cyanoacetyl)Amino]-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxylate
CAS No.	669753-36-0
Molecular Formula	C15H18N2O3S
Molecular Weight	306.38 g/mol
Synonyms	Ethyl 2-[(cyanoacetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-[(Cyanoacetyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid ethyl ester; 669753-36-0; Ethyl 2-(2-cyanoacetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate; 4H-Cyclohepta[b]thiophene-3-carboxylic acid, 2-[(cyanoacetyl)amino]-5,6,7,8-tetrahydro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-[(Cyanoacetyl)Amino]-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.