Description

Indolizine, Octahydro-2,2,5-Trimethyl-, (5R,8Ar)-Rel- (9Ci) is a high-purity, stereochemically defined indolizine derivative, a privileged scaffold in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the construction of complex molecular architectures with precise stereochemical control for research and development. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is critical for biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Material Science Research: Investigated as a core structure for developing organic semiconductors, liquid crystals, or fluorescent dyes due to the indolizine core's electronic properties.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in methodology development and exploring new chemical space for bioactive molecules.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex, stereochemically pure aroma chemicals.

Basic Information

Product Name	Indolizine, Octahydro-2,2,5-Trimethyl-, (5R,8Ar)-Rel- (9Ci)
CAS No.	669073-79-4
Molecular Formula	C12H21N
Molecular Weight	179.30 g/mol
Synonyms	rel-(5R,8aR)-Octahydro-2,2,5-trimethylindolizine; (5R,8aR)-rel-2,2,5-Trimethyloctahydroindolizine; 2,2,5-Trimethyloctahydroindolizine, (5R,8aR)-rel-; Octahydro-2,2,5-trimethylindolizine, (5R,8aR)-rel-; Indolizine, octahydro-2,2,5-trimethyl-, (5R,8aR)-rel-; Chiral Indolizine Derivative; 669073-79-4
EINECS	Contact for details

Quality Control

Our production of Indolizine, Octahydro-2,2,5-Trimethyl-, (5R,8Ar)-Rel- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized using advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.