Description

4-Bromo-2-(Piperazin-1-Yl)Thiazole is a high-purity, heterocyclic organic compound featuring a thiazole core substituted with bromine and a piperazine moiety. This specific molecular architecture makes it a valuable and versatile pharmaceutical intermediate and research chemical for medicinal chemistry programs. It is primarily sought after by R&D teams and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and as a key building block in drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and combinatorial chemistry to develop new chemical entities with optimized biological activity.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex APIs, leveraging its reactive bromine and secondary amine for further functionalization.
• Biochemical Tool Compound: Can be utilized in biochemical assays and as a ligand in the development of pharmacological probes for target validation.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents and pesticides.
• Material Science Precursor: May be employed in the synthesis of specialized organic materials, such as ligands for catalysts or components for organic electronics.

Basic Information

Product Name	4-Bromo-2-(Piperazin-1-Yl)Thiazole
CAS No.	668484-59-1
Molecular Formula	C7H10BrN3S
Molecular Weight	248.15 g/mol
Synonyms	4-Bromo-2-(1-piperazinyl)-1,3-thiazole; 2-(Piperazin-1-yl)-4-bromothiazole; 4-Bromo-2-piperazin-1-yl-1,3-thiazole; 4-Bromo-2-piperazinylthiazole; Thiazole, 4-bromo-2-(1-piperazinyl)-; 668484-59-1; 4-Bromo-2-(piperazin-1-yl)thiazole; 4-Bromo-2-(piperazin-1-yl)-1,3-thiazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Piperazin-1-Yl)Thiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports its use in cGMP and research applications where traceability and consistency are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.