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(4-Methyl-2-[3-(Trifluoromethyl)Phenyl]-1,3-Thiazol-5-Yl)Methanol CAS NO 668477-94-9


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CAS No.:668477-94-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(4-Methyl-2-[3-(Trifluoromethyl)Phenyl]-1,3-Thiazol-5-Yl)Methanol is a high-value, fluorinated thiazole derivative serving as a critical advanced intermediate in modern organic synthesis. Its core value proposition lies in its unique molecular architecture, which combines a thiazole heterocycle with a trifluoromethylphenyl group, enabling the development of novel compounds with enhanced properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
  • Agrochemical Research: Used in the development of next-generation pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
  • Material Science Precursor: Serves as a monomer or functional additive in the creation of specialty polymers and advanced materials with specific optical or electronic properties.
  • Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
  • Fluorine Chemistry: A valuable substrate for further fluorination reactions and the study of structure-activity relationships (SAR) in fluorinated molecules.

Basic Information

Product Name (4-Methyl-2-[3-(Trifluoromethyl)Phenyl]-1,3-Thiazol-5-Yl)Methanol
CAS No. 668477-94-9
Molecular Formula C12H10F3NOS
Molecular Weight 273.27 g/mol
Synonyms 5-(Hydroxymethyl)-4-methyl-2-[3-(trifluoromethyl)phenyl]thiazole; [4-Methyl-2-(3-trifluoromethylphenyl)-1,3-thiazol-5-yl]methanol; 2-(3-(Trifluoromethyl)phenyl)-4-methylthiazole-5-methanol; 5-(Hydroxymethyl)-4-methyl-2-(α,α,α-trifluoro-m-tolyl)thiazole; (4-Methyl-2-(3-trifluoromethylphenyl)thiazol-5-yl)methanol
EINECS Contact for details

Quality Control

Our (4-Methyl-2-[3-(Trifluoromethyl)Phenyl]-1,3-Thiazol-5-Yl)Methanol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, assay, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for research, pilot, or commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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