Description

Methyl 3-[(3-Formyl-1H-Indol-1-Yl)Methyl]Benzoate is a high-purity, advanced pharmaceutical intermediate characterized by its indole and benzoate functional groups. This compound matters for its critical role as a versatile building block in the synthesis of complex bioactive molecules, enabling the development of new therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, particularly for developing oncology and central nervous system (CNS) targeted drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic entities.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial R&D.
• Bioconjugation & Probe Development: Utilized in the creation of chemical probes and labeled compounds for biochemical and diagnostic applications.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	Methyl 3-[(3-Formyl-1H-Indol-1-Yl)Methyl]Benzoate
CAS No.	667435-96-3
Molecular Formula	C18H15NO3
Molecular Weight	293.32 g/mol
Synonyms	1H-Indole-3-carboxaldehyde, 1-[(3-(methoxycarbonyl)phenyl)methyl]-; Methyl 3-[(3-formyl-1H-indol-1-yl)methyl]benzoate; 3-[(3-Formyl-1H-indol-1-yl)methyl]benzoic acid methyl ester; 1-[(3-Methoxycarbonylbenzyl)]indole-3-carboxaldehyde; Benzoic acid, 3-[(3-formyl-1H-indol-1-yl)methyl]-, methyl ester; 667435-96-3; 1-(3-Carbomethoxybenzyl)indole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our Methyl 3-[(3-Formyl-1H-Indol-1-Yl)Methyl]Benzoate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.