Description

8-Bromo-7-(But-2-Ynyl)-3-Methyl-1H-Purine-2,6(3H,7H)-Dione is a high-purity, functionalized purine derivative, a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceutical agents and bioactive molecules, enabling targeted molecular modifications. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential adenosine receptor modulators and kinase inhibitors.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially those targeting purinergic signaling pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Biochemical Tool Compound: Serves as a probe in biochemical assays to study enzyme mechanisms, particularly those involving purine-based substrates.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and other advanced synthetic methodologies to construct complex heterocyclic systems.
• Academic & Industrial R&D: Essential for exploratory research in universities and corporate R&D labs focusing on novel therapeutic areas.

Basic Information

Product Name	8-Bromo-7-(But-2-Ynyl)-3-Methyl-1H-Purine-2,6(3H,7H)-Dione
CAS No.	666816-98-4
Molecular Formula	C₁₀H₉BrN₄O₂
Molecular Weight	297.11 g/mol
Synonyms	8-Bromo-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 8-Bromo-7-(2-butynyl)-3-methylxanthine; 8-Bromo-7-(but-2-ynyl)-3-methylxanthine; 3-Methyl-8-bromo-7-(2-butynyl)xanthine; 8-Bromo-3-methyl-7-(2-butyn-1-yl)xanthine; 8-Bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6-dione; Xanthine, 8-bromo-7-(2-butynyl)-3-methyl-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.