Description

Ethyl 3-(Hydroxymethyl)-1H-Indole-2-Carboxylate is a versatile indole derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a hydroxymethyl and an ester group, makes it a valuable precursor for constructing complex heterocyclic frameworks. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Organic Synthesis Building Block: Employed in the construction of more complex indole alkaloids and heterocyclic compounds for material science and chemical biology.
• Academic & R&D Laboratories: Serves as a standard reagent for methodological development and exploration of new chemical reactions in medicinal chemistry.

Basic Information

Product Name	Ethyl 3-(Hydroxymethyl)-1H-Indole-2-Carboxylate
CAS No.	666752-02-9
Molecular Formula	C₁₂H₁₃NO₃
Molecular Weight	219.24 g/mol
Synonyms	Ethyl 3-(hydroxymethyl)-1H-indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 3-(hydroxymethyl)-, ethyl ester; 3-(Hydroxymethyl)-1H-indole-2-carboxylic acid ethyl ester; Ethyl 3-hydroxymethylindole-2-carboxylate; 2-Carbethoxy-3-hydroxymethylindole; CAS 666752-02-9
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Hydroxymethyl)-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.