Description

4,7-Methano-2H-Indazole-5,6-Diol,2-Ethyl-4,5,6,7-Tetrahydro-,(4R,5R,6S,7S)-Rel-(9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex, polycyclic structure with multiple chiral centers makes it a valuable building block for the development of novel, biologically active compounds. This material is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and the synthesis of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing complex molecular libraries in drug discovery programs.
• Asymmetric Synthesis: Employed in stereoselective synthesis due to its defined (4R,5R,6S,7S) configuration for creating enantiomerically pure compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study enzyme function and biological pathways.
• Advanced Material Synthesis: Potential application as a monomer or precursor for specialized polymers and advanced organic materials requiring specific stereochemistry.

Basic Information

Product Name	4,7-Methano-2H-Indazole-5,6-Diol,2-Ethyl-4,5,6,7-Tetrahydro-,(4R,5R,6S,7S)-Rel-(9Ci)
CAS No.	664333-98-6
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	2-Ethyl-4,5,6,7-tetrahydro-4,7-methano-2H-indazole-5,6-diol; (4R,5R,6S,7S)-rel-2-Ethyl-4,5,6,7-tetrahydro-4,7-methano-1H-indazole-5,6-diol; 2-Ethyl-4,5,6,7-tetrahydro-4,7-methano-1H-indazole-5,6-diol (rel-(4R,5R,6S,7S)-); 4,7-Methano-1H-indazole-5,6-diol, 2-ethyl-4,5,6,7-tetrahydro-, (4R,5R,6S,7S)-rel-; 664333-98-6; rel-(4R,5R,6S,7S)-2-Ethyl-4,5,6,7-tetrahydro-4,7-methano-2H-indazole-5,6-diol
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP standards for pharmaceutical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccant packs or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (rel-(4R,5R,6S,7S)-)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.