Description

4,7-Methano-1H-Indazole-5,6-Diol,1-Ethyl-4,5,6,7-Tetrahydro-,(4R,5R,6S,7S)-Rel-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise control over the final product's stereochemistry and efficacy. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D for new drug candidates. The product is supplied under the CAS number 664333-97-5.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery programs.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for target molecules.
• Asymmetric Synthesis: Utilized in catalytic or stoichiometric asymmetric transformations to construct complex molecular architectures.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probes: Potential use in the development of molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Details
Product Name	4,7-Methano-1H-Indazole-5,6-Diol,1-Ethyl-4,5,6,7-Tetrahydro-,(4R,5R,6S,7S)-Rel-(9Ci)
CAS No.	664333-97-5
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	1-Ethyl-4,5,6,7-tetrahydro-4,7-methano-1H-indazole-5,6-diol; (4R,5R,6S,7S)-rel-1-Ethyl-4,5,6,7-tetrahydro-4,7-methano-1H-indazole-5,6-diol; 1-Ethyl-4,5,6,7-tetrahydro-4,7-methanoindazole-5,6-diol; 4,7-Methano-1H-indazole-5,6-diol, 1-ethyl-4,5,6,7-tetrahydro-, (4R,5R,6S,7S)-rel-; 664333-97-5; rel-(4R,5R,6S,7S)-1-Ethyl-4,5,6,7-tetrahydro-4,7-methano-1H-indazole-5,6-diol
EINECS	Contact for details

Quality Control

Our 4,7-Methano-1H-Indazole-5,6-Diol,1-Ethyl-4,5,6,7-Tetrahydro-,(4R,5R,6S,7S)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting purity, stereochemical composition, and other critical parameters are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.