Description

5-(Pentafluorothio)-1H-Benzimidazole, 5-(Pentafluorosulphanyl)-1H-Benzimidazole is a high-value, fluorinated benzimidazole derivative distinguished by its unique pentafluorosulfanyl (SF5) functional group. This compound serves as a critical advanced pharmaceutical intermediate and specialty chemical building block, enabling the synthesis of novel molecules with enhanced properties. It is primarily sought after by R&D and production teams in the agrochemical, pharmaceutical, and materials science industries for developing next-generation products.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders, leveraging the SF5 group's metabolic stability and lipophilicity.
• Agrochemical Research: Building block for novel herbicides, fungicides, and insecticides, where the pentafluorosulfanyl moiety can improve biological activity and environmental persistence profiles.
• Ligand & Catalyst Development: Used in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Functional Materials Synthesis: Intermediate for advanced polymers, liquid crystals, and electronic materials that benefit from the unique electronic and steric properties of the SF5 group.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or tagging agent in the development of chemical probes and bio-conjugation tools.

Basic Information

Product Name	5-(Pentafluorothio)-1H-Benzimidazole, 5-(Pentafluorosulphanyl)-1H-Benzimidazole
CAS No.	663179-60-0
Molecular Formula	C7H3F5N2S
Molecular Weight	242.17 g/mol
Synonyms	5-(Pentafluorosulfanyl)-1H-benzimidazole; 5-(SF5)-1H-Benzimidazole; 1H-Benzimidazole, 5-(pentafluorothio)-; 5-Pentafluorosulfanylbenzimidazole; 5-(Pentafluorosulphanyl)benzimidazole; Benzimidazole, 5-(pentafluorosulfanyl)-; 5-(Pentafluorosulfanyl)-1H-benzo[d]imidazole
EINECS	Contact for details

Quality Control

Our production of 5-(Pentafluorothio)-1H-Benzimidazole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system supports traceability and meets the rigorous standards required for advanced R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.