Description

1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-[2-[(2-Aminoethyl)Amino]Ethyl]Hexahydro-2-Oxo-, (3As,4S,6Ar)- is a complex, high-purity heterocyclic compound with a defined stereochemistry, serving as a critical advanced intermediate in sophisticated organic syntheses. Its precise molecular architecture makes it an invaluable building block for research and development in targeted pharmaceutical applications. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for complex therapeutic targets.
• Bioconjugation & Probe Development: Utilized in the creation of specialized probes, linkers, or tags for biochemical research and diagnostic assay development due to its functional groups.
• Peptidomimetic & Drug Discovery: Serves as a constrained scaffold or a modified amino acid analog in medicinal chemistry programs aimed at improving drug potency and metabolic stability.
• Chemical Biology Research: Employed in studying enzyme mechanisms or protein-ligand interactions where its specific structure can act as an inhibitor or a substrate analog.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific molecules under cGMP conditions.

Basic Information

Product Name	1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-[2-[(2-Aminoethyl)Amino]Ethyl]Hexahydro-2-Oxo-, (3As,4S,6Ar)-
CAS No.	663176-53-2
Molecular Formula	C15H25N5O2S
Molecular Weight	339.46 g/mol
Synonyms	(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide, N-[2-[(2-aminoethyl)amino]ethyl]-; Biotin-PEG2-Amine; Biotin-amido-PEG2-amine; Biotin-PEG2-NH2; Biotinylated Polyethylene Glycol Amine; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-[2-(2-aminoethylamino)ethylamino]ethyl]pentanamide (related form); Biotin-PEG2-C2-amine.
EINECS	Contact for details

Quality Control

Our 1H-Thieno[3,4-D]Imidazole-4-Pentanamide derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets exacting standards suitable for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.