Description

Amg 517 CAS NO 659730-32-2 is a high-purity, small molecule compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical tool for researchers investigating specific biological pathways and disease mechanisms. It is primarily utilized by pharmaceutical companies, biotechnology firms, and academic research institutions engaged in drug discovery and preclinical studies. Our supply ensures consistent quality and reliable availability to support critical R&D timelines.

Application

• Pharmaceutical Research & Development: A key intermediate or active pharmaceutical ingredient (API) in the discovery and development of novel therapeutic agents.
• Biochemical Assay Development: Used as a reference standard or probe compound in high-throughput screening (HTS) and in vitro assay systems to study target engagement and efficacy.
• Preclinical Studies: Employed in animal model studies to evaluate pharmacokinetics, pharmacodynamics, and preliminary safety profiles of candidate drug molecules.
• Chemical Biology: Serves as a molecular tool to modulate specific protein functions, aiding in the understanding of complex cellular signaling pathways.
• Reference Standard Manufacturing: Supplied as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratory settings.

Basic Information

Product Name	Amg 517
CAS No.	659730-32-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AMG-517; AMG 517; 659730-32-2; (S)-AMG 517; (S)-N-[4-(3-Chlorophenyl)-3-hydroxy-2,2-dimethyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-7-yl]-N-methylmethanesulfonamide; AMG517
EINECS	Contact for details

Quality Control

Our Amg 517 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade specifications. Our quality commitment supports the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.