Description

(2E)-n-(2,3-Dihydro-1H-Indol-1-Ylcarbonothioyl)-3-(Thiophen-2-Yl)Prop-2-Enamide is a specialized organic compound featuring a unique molecular scaffold combining indoline and thiophene moieties. This structural complexity makes it a valuable advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery programs targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those with heterocyclic core structures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new molecules with optimized biological activity.
• Chemical Biology Probe: Acts as a tool compound for investigating specific enzyme interactions or biological pathways in academic and industrial research.
• Organic Synthesis Reference Standard: Provides a high-purity standard for analytical method development and validation in QC laboratories.
• Custom Synthesis: Employed as a starting material for the contract manufacturing of complex, proprietary molecules for clinical trials.

Basic Information

Item	Details
Product Name	(2E)-n-(2,3-Dihydro-1H-Indol-1-Ylcarbonothioyl)-3-(Thiophen-2-Yl)Prop-2-Enamide
CAS No.	658071-49-9
Molecular Formula	C16H14N2OS2
Molecular Weight	314.42 g/mol
Synonyms	(E)-N-(2,3-Dihydro-1H-indole-1-carbonothioyl)-3-(thiophen-2-yl)prop-2-enamide; 1-[(2E)-3-(2-Thienyl)-2-propenoyl]thiocarbamoyl-2,3-dihydro-1H-indole; 658071-49-9; (2E)-N-(2,3-Dihydro-1H-indol-1-ylcarbonothioyl)-3-(2-thienyl)-2-propenamide; (2E)-3-(Thiophen-2-yl)-N-(2,3-dihydro-1H-indole-1-carbonothioyl)acrylamide
EINECS	Contact for details

Quality Control

Our (2E)-n-(2,3-Dihydro-1H-Indol-1-Ylcarbonothioyl)-3-(Thiophen-2-Yl)Prop-2-Enamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.